What is a chemical combination of two or more elements referred to as?

The term that describes a chemical combination of two or more elements is a compound. Compounds are substances formed when two or more elements chemically bond together, resulting in distinct physical and chemical properties that are different from the individual elements. For instance, water is a compound made of hydrogen and oxygen.

A mixture refers to a physical combination of two or more substances where each retains its own properties; this is a key distinction from compounds, where the elements cannot be easily separated by physical means. An alloy is a specific type of mixture made from two or more metals or a metal and another element, which again differs from a compound, as the metals do not chemically combine to form a new substance. A solution is a homogeneous mixture where a solute is dissolved in a solvent, typically involving a combination of liquids or gases rather than the formation of a new compound through chemical bonding. Thus, in this context, a compound is the correct term to define the chemical combination of elements.